$136.11+0.68 (+0.50%)
Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. in the Healthcare sector is trading at $136.11 with a market capitalization of $7.1B. Wall Street consensus targets $133.31 (13 analysts), implying a -2.1% move over the next 12 months. The stock is currently near its 52-week high of $143.29, remaining 42.2% above its 200-day moving average. On fundamentals, Piotroski 4/9 shows mixed financial quality, Altman Z in the safe zone. The Whystock Score of 95/100 reflects bullish alignment across trend, valuation and analyst targets.
| Metric (USD) | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|
| Total Revenue | $56.37M↑ | $7.44M↑ | $4.71M↓ | $5.55M↓ | $28.32M |
| Gross Profit | — | — | — | — | — |
| Operating Income | -$3.65M↑ | -$50.35M↓ | -$46.42M↓ | -$42.04M↓ | -$19.31M |
| Net Income | $3.78M↑ | -$44.38M↓ | -$39.34M↓ | -$34.77M↓ | -$11.65M |
Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and ol...
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After a very large three year return, Protagonist Therapeutics now faces a valuation debate, with the stock’s strong share price performance sitting alongside a mixed read from the latest valuation checks. Over three years, Protagonist Therapeutics has delivered a return of roughly 7x, which puts extra focus on whether the current price already builds in much of the good news. The launch of Icotyde and the FDA priority review for rusfertide can support higher revenue expectations, while...
Protagonist Therapeutics (PTGX) has been in focus after two key milestones: the FDA approval and U.S. launch of Icotyde for psoriasis, and a priority review for rusfertide in polycythemia vera with an August 2026 decision expected. See our latest analysis for Protagonist Therapeutics. Protagonist Therapeutics’ share price has surged in recent months, with a 60.67% year to date share price return and a very large 3 year total shareholder return, as investors focus on Icotyde’s launch and...
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