$14.88-0.42 (-2.75%)
Ultragenyx Pharmaceutical Inc., a biopharmaceutical company, focuses on the identification, acquisition, development, and commercialization of novel products for the treatment of rare and ultra-rare genetic diseases in North America, Latin America, Europe, the Middle East, Africa, and the Asia-Pacific.
Ultragenyx Pharmaceutical Inc. in the Healthcare sector is trading at $14.88 with a market capitalization of $1.5B. Wall Street consensus targets $27.00 (19 analysts), implying a +81.5% move over the next 12 months. The stock is currently near its 52-week low of $13.81, remaining 42.6% below its 200-day moving average. On fundamentals, Piotroski 6/9 shows mixed financial quality, Altman Z in the distress zone. Risk note: RSI 21 is oversold, raising the odds of a near-term bounce; MACD remains below its signal line. The Whystock Score of 50/100 suggests a balanced risk-reward profile.
| Metric (USD) | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 |
|---|---|---|---|---|---|
| Total Revenue | $214.00M↑ | $136.00M↓ | $207.28M↑ | $159.93M↓ | $167.00M |
| Gross Profit | $180.00M↑ | $106.00M↓ | $177.93M↑ | $131.94M↓ | $144.00M |
| Operating Income | -$75.00M↑ | -$169.00M↓ | -$113.28M↑ | -$170.89M↓ | -$108.00M |
| Net Income | -$92.00M↑ | -$185.00M↓ | -$128.56M↑ | -$180.41M↓ | -$115.00M |
Ultragenyx Pharmaceutical Inc., a biopharmaceutical company, focuses on the identification, acquisition, development, and commercialization of novel products for the treatment of rare and ultra-rare genetic diseases in North America, Latin America, E...

In early September 2026, Ultragenyx Pharmaceutical announced that its Phase 3 Aspire trial of apazunersen (GTX-102) in Angelman syndrome failed to meet its primary and key secondary cognitive and functional endpoints, prompting a review of the program and planned significant expense reductions. On the same day, the FDA confirmed that Ultragenyx’s newly approved GENGLYCOS gene therapy for glycogen storage disease type Ia qualifies for a rare pediatric disease priority review voucher,...

Ultragenyx Pharmaceutical stock is under pressure after a multi year slide in returns, yet current market multiples still screen as expensive and the broader valuation checks send a mixed message. With fresh clinical setbacks alongside some positive data elsewhere in the pipeline, investors face conflicting signals about what the current price really reflects. Over the past 5 years the share price has fallen about 85%, which points to a sharp reset in market expectations for Ultragenyx...
Wall Street removed the Angelman program from valuation models, slashing price targets by as much as 76% and issuing multiple downgrades.

NIO, Ultragenyx Pharmaceutical and McDonald's slipped to annual lows on Thursday amid company-related pressures and Wall Street pessimism around the stocks.
Zanvastro is now approved for children and adults with Alexander disease, a rare and often fatal brain condition that affects fewer than one in a million people.