DNLI

$20.71

Post-MarketAs of Mar 17, 8:00 PM UTC

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases.

Historical Price

Price (Line)
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Peer Comparison

JNJUNHPFE

Whystock Valuation Model

Calculated using a trailing P/E relative model adjusted by sector ROE and historical growth.
Current Price$20.71
Potential Upside
5%
Whystock Fair Value$21.75
Price
UndervaluedFair ValueOvervalued

Fundamentals

SectorHealthcare
IndustryBiotechnology

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflamma...

Market Cap
Total dollar market value of a company's outstanding shares of stock (Price * Shares).
$3.28B
P/E Ratio
Priced for growth. Investors expect sustained double-digit expansion.
-
Beta
High-beta play. Expect amplified moves vs. the broad market.
1.08
Div Yield
Low to zero yield. Return is entirely dependent on price appreciation.
0.00%
ROIC
Average efficiency. Growth may require heavy reinvestment.
-45.69%
Quick Ratio
Pristine liquidity. Sufficient cash to cover all near-term obligations.
8.85

Recent News

MarketBeat
Mar 15, 2026

Denali Therapeutics Teases April 5 FDA Decision for Tivi as Launch Plans and Pipeline Catalysts Build

Denali Therapeutics (NASDAQ:DNLI) executives outlined near-term regulatory milestones, commercial launch preparations, and a broadening pipeline during a discussion hosted by Leerink Partners analyst Marc Goodman. Chief Executive Officer Ryan Watts and Chief Commercial Officer Katie Peng focused on

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
Simply Wall St.
Mar 13, 2026

Denali Therapeutics (DNLI) Is Up 5.1% After Highlighting Tividenofusp Alfa Ahead Of FDA Decision – Has The Bull Case Changed?

Earlier in March 2026, Denali Therapeutics Inc. presented at the UBS Biotech Summit and Jefferies Biotech on the Beach Summit in Miami, highlighting its rare disease programs and blood–brain barrier platform. Investor attention is increasingly centered on tividenofusp alfa for Hunter syndrome, with an upcoming FDA action date viewed as a key test of Denali’s therapeutic approach. We’ll now examine how anticipation around the FDA decision on tividenofusp alfa could influence Denali’s...

NEUTRAL
Neutral flow. Standard news cycle with no clear sentiment tilt.
Simply Wall St.
Mar 13, 2026

Assessing Denali Therapeutics (DNLI) Valuation After A Strong Year Of Share Price Gains

Denali Therapeutics (DNLI) has been drawing attention after recent share price moves, with the stock up 27.2% year to date and delivering a 39% total return over the past year. This performance has prompted fresh investor scrutiny. See our latest analysis for Denali Therapeutics. The recent 7 day share price return of 5.1% and 90 day share price return of 15.1%, against a 1 year total shareholder return of 39%, point to momentum that has picked up in the short term after a weaker multi year...

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
Zacks
Mar 11, 2026

Denali Gains 11.8% in a Month: Buy, Sell or Hold the Stock?

DNLI stock jumps as investors eye an April 5, 2026, FDA decision on tividenofusp alfa for Hunter syndrome, a key catalyst for growth.

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
MarketBeat
Feb 5, 2026

Denali Therapeutics Showcases ETV Data at WORLD: TIVI PDUFA Near, DNL126 Hits 80% CSF Drop

Denali Therapeutics (NASDAQ:DNLI) used an analyst call from the 2026 WORLD Symposium in San Diego to highlight new and updated data from its enzyme transport vehicle (ETV) franchise, including clinical follow-up for tividenofusp alfa (TIVI) in Hunter syndrome (MPS II), preliminary Phase 1/2 biomarke

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.