SION

$35.84

Market ClosedAs of Mar 17, 8:00 PM UTC

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF).

Historical Price

Price (Line)
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Peer Comparison

JNJUNHPFE

Whystock Valuation Model

Calculated using a trailing P/E relative model adjusted by sector ROE and historical growth.
Current Price$35.84
Potential Upside
5%
Whystock Fair Value$37.63
Price
UndervaluedFair ValueOvervalued

Fundamentals

SectorHealthcare
IndustryBiotechnology

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmemb...

Market Cap
Total dollar market value of a company's outstanding shares of stock (Price * Shares).
$1.61B
P/E Ratio
Priced for growth. Investors expect sustained double-digit expansion.
-
Beta
High-beta play. Expect amplified moves vs. the broad market.
-
Div Yield
Low to zero yield. Return is entirely dependent on price appreciation.
0.00%
ROIC
Average efficiency. Growth may require heavy reinvestment.
-31.79%
Quick Ratio
Pristine liquidity. Sufficient cash to cover all near-term obligations.
20.14

Recent News

Motley Fool
Mar 15, 2026

This Investor Sold $5 Million of a Biotech Stock Up 118% in a Year, but Here's Why It Still Seems Bullish on Shares

This biotech firm develops therapies targeting cystic fibrosis, with shares up nearly 90% year-over-year as of the latest filing.

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
Simply Wall St.
Feb 27, 2026

Assessing Sionna Therapeutics (SION) Valuation As Premium P/B Meets Cooling Share Price Momentum

Sionna Therapeutics (SION) has drawn attention after recent trading, with the share price closing at $38. For investors tracking performance, returns over the past week, month and past 3 months show mixed moves. See our latest analysis for Sionna Therapeutics. That recent softness in the 1 month share price return of 12.44% and 3 month share price return of 12.78%, despite a 1 year total shareholder return of around 2.6x, suggests some of the earlier enthusiasm has cooled as investors...

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
MarketBeat
Feb 15, 2026

Sionna Therapeutics Maps Mid-2026 CF Catalysts, Highlights NBD1 Stabilizers at Guggenheim Summit

Sionna Therapeutics (NASDAQ:SION) used its presentation at the Guggenheim Emerging Outlook Biotech Summit 2026 to outline its strategy to develop next-generation cystic fibrosis (CF) therapies centered on NBD1 stabilization, and to preview multiple mid-2026 clinical catalysts. Company background an

NEUTRAL
Neutral flow. Standard news cycle with no clear sentiment tilt.
Motley Fool
Jan 13, 2026

Sionna Therapeutics Chief Legal Officer Caps Off Strong 2025 with Sale of Over 10,000 Shares

After having a successful IPO less than a year ago, this biotech innovator had notable insider transactions to close out 2025.

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
Simply Wall St.
Jan 12, 2026

Assessing Sionna Therapeutics (SION) Valuation After Recent Share Price Swings And Premium P/B Multiple

What Sionna Therapeutics’ Recent Price Move Means for Investors Sionna Therapeutics (SION) shares recently closed at $39.25, with the stock showing mixed short term moves, including a 7.24% gain over the past day and a negative return over the past month. See our latest analysis for Sionna Therapeutics. Looking beyond the latest move, Sionna Therapeutics has a 90 day share price return of 33.91% but a 30 day share price return of 8.23%. This suggests recent momentum has cooled after a...

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.