SPRB

$64.30

Market ClosedAs of Mar 17, 8:00 PM UTC

Spruce Biosciences, Inc.

Historical Price

Price (Line)
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Peer Comparison

JNJUNHPFE

Whystock Valuation Model

Calculated using a trailing P/E relative model adjusted by sector ROE and historical growth.
Current Price$64.30
Potential Upside
5%
Whystock Fair Value$67.52
Price
UndervaluedFair ValueOvervalued

Fundamentals

SectorHealthcare
IndustryBiotechnology

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, ...

Market Cap
Total dollar market value of a company's outstanding shares of stock (Price * Shares).
$68.82M
P/E Ratio
Priced for growth. Investors expect sustained double-digit expansion.
-
Beta
High-beta play. Expect amplified moves vs. the broad market.
3.82
Div Yield
Low to zero yield. Return is entirely dependent on price appreciation.
0.00%
ROIC
Average efficiency. Growth may require heavy reinvestment.
-109.24%
Quick Ratio
Pristine liquidity. Sufficient cash to cover all near-term obligations.
5.11

Recent News

Insider Monkey
Mar 17, 2026

Spruce Biosciences (SPRB) Appoints Dale Hooks as CCO and Reports Narrowed $39M 2025 Net Loss

Spruce Biosciences Inc. (NASDAQ:SPRB) is one of the best hot stocks to buy according to analysts. On March 9, Spruce Biosciences appointed Dale Hooks as Chief Commercial Officer to lead the company’s transition toward its next phase of growth. Hooks brings nearly 35 years of biopharmaceutical experience to the role, having overseen 21 new product […]

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
Insider Monkey
Mar 4, 2026

Spruce Biosciences (SPRB) Gains FDA Support for Accelerated Approval Pathway

Spruce Biosciences Inc. (NASDAQ:SPRB) is one of the most promising micro-cap stocks according to analysts. On February 18, Spruce Biosciences recently concluded successful Type B meetings with the FDA, clearing a path for the BLA submission of tralesinidase alfa enzyme replacement therapy (TA-ERT). The Agency confirmed that existing clinical and natural history data could support […]

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
MarketBeat
Mar 1, 2026

Spruce Biosciences Touts MPS IIIB Data, Targets Q4 BLA Submission at Oppenheimer Conference

Executives from Spruce Biosciences (NASDAQ:SPRB) outlined regulatory plans, clinical data highlights, and commercial considerations for the company’s lead program in Sanfilippo syndrome type B (MPS IIIB) during a fireside chat at Oppenheimer’s 36th Annual Healthcare and Life Sciences Conference. Pr

NEUTRAL
Neutral flow. Standard news cycle with no clear sentiment tilt.
TipRanks
Dec 24, 2025

Spruce Biosciences initiated with an Outperform at Oppenheimer

Oppenheimer initiated coverage of Spruce Biosciences (SPRB) with an Outperform rating and $283 price target. Further to FDA’s confirmation that existing and what the firm views as “compelling” clinical biomarker data could drive accelerated approval, recent Breakthrough Therapy designation bolsters the firm’s conviction ahead of next year’s anticipated approval for Sanfilippo type B syndrome, the analyst tells investors. The firm, which sees “considerable upside for this underappreciated story,”

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.
The Fly
Dec 23, 2025

Coty downgraded, Spruce Biosciences initiated: Wall Street's top analyst calls

Coty downgraded, Spruce Biosciences initiated: Wall Street's top analyst calls

BULLISH
Positive press. Headlines skewed toward growth and analyst upgrades.